What antibiotics are used to treat prostatitis?

In some cases, antibiotics are included in the treatment regimen for prostatitis. The choice of a particular drug depends on several factors. Antibacterial therapy of acute and chronic forms of the disease has some significant differences.

Antibiotic intake is an important component in the successful treatment of acute and chronic prostatitis. The success of treatment largely depends on the proper selection of the drug and its administration scheme.

Indications for the appointment and effect of antibiotics for prostatitis

Antibiotics are prescribed when it is clear that prostate inflammation is caused by an infection. This applies not only to the acute course of the disease, when the expressed symptoms forced to provide emergency assistance. Chronic bacterial prostatitis, which occurs with a mild clinical picture or no symptoms at all, also requires antibiotic therapy.

The indication for taking antibiotics is not a specific symptom, but laboratory data indicate the presence of an infection.

To do this, use PCR (polymerase chain reaction method), which with high accuracy allows you to identify infections transmitted through sexual contact, as well as the study of urine and prostate secretions, which allows you to detect the presence of bacteria.

Sometimes infectious inflammation continues to be hidden - in this case, the level of leukocytes in the secretions of the gland does not exceed normal levels. To determine if there is an infection, the doctor prescribes a test dose of antibiotics. After a week of taking this drug, the analysis is taken again, and if the level of leukocytes exceeds 25 units, we are talking about a hidden course of infectious lesions of the prostate. In this case, antibiotics become mandatory.

The choice of antibiotics to treat prostate inflammation depends on several factors. The main thing is which bacteria have been identified and which drugs they are sensitive to. There is no universal cure.

The principle of action of antibiotics depends on the type of drug used, the form of the disease and the inflammatory agent. However, the general essence can be reduced to several levels:

  1. Penetration of the drug into the blood through assimilation through the gastrointestinal tract or through intravenous administration.
  2. Penetration of the active substance into the tissues of the prostate gland and the destruction of disease -causing agents.
  3. The effect of accumulation in the glandular tissue, which allows you to fight infection on an ongoing basis.

The last step is very important, as some antibiotics are only bacteriostatic in nature. This means it only affects the dividing cells. At the same time, cells that are in an anaerobic state remain unnoticed by them. If the active ingredient of the drug does not accumulate in the prostate tissue, then the bacteria that have left the anaerobic state will quickly negate the overall effect of the treatment.

There are bacteria that are very resistant to drugs. This is probably the most common causative agent of prostatitis, for example, Escherichia coli. They build hard capsules and biofilms that reduce the effects of active drug ingredients. In this case, it is necessary that the drugs have the ability to destroy the protective shell of these bacteria. It is also important to take medications until the end, even if the symptoms of the disease have disappeared.

Group of antibacterial agents for the treatment of prostatitis

There are several groups of antibiotics that are effective (singly or in combination) against bacteria that cause inflammation of the prostate gland. The choice of a particular group of drugs depends on several factors: "weak spots" in the identified bacteria, the comorbidities of the patient, the severity of the course of prostatitis, the form and side effects of the drug.

The main groups of antibacterial drugs for prostatitis include:

  • tetracycline;
  • penicillin;
  • cephalosporine;
  • macrolide;
  • fluoroquinolones.

Tetracycline series

Antibiotics of this group have bacteriostatic effects, which means that they inhibit cell division, growth and development.

Do not think that bacteriostatic drugs are ineffective. This effect is sufficient to eliminate the infection, provided the patient does not have weakened immunity.

Such drugs disrupt the relationship between RNA (which "gives instructions" for the development and division of pathogens) and ribosomes (which carry out these "instructions"), thus suppressing the production of proteins-the building blocks for new cells.

men taking antibiotics for prostatitis

Drugs of this group are effective in combating the following pathogens:

  • mycoplasmas;
  • ureaplasma;
  • chlamydia;
  • enterococci;
  • enterobacteria;
  • klebsiella;
  • pseudomonas;
  • seration;
  • coli.

Drugs in this group are prescribed selectively because of the large list of side effects.

Penicillin series

Preparations of this group also have a bacteriostatic effect, affecting the dividing bacteria. However, they have a different principle of action: they stop the production of the main component of the bacterial cell wall - peptidoglycans.

Since there are many bacteria that have developed resistance to antibiotics in this group, a protected penicillin subgroup has been developed.

These antibiotics are effective in treating inflammation caused by the following bacteria:

  • gonococci;
  • staphylococci;
  • enterobacteria;
  • Proteus;
  • klebsiella;
  • seration;
  • coli.

Drugs in this group are prescribed with caution because of the high risk of allergic reactions. To treat prostate inflammation, drugs based on oxacillin, ampicillin and amoxicillin are prescribed.


This is a powerful bactericidal drug that not only inhibits cell division, but destroys it. This occurs in two steps: disruption of peptidoglycan production (destruction of cell walls) and enzyme release.

Drugs in this group are effective against:

  • gonococci;
  • enterobacteria;
  • Proteus bacteria;
  • Klebsiella;
  • coli.

Drugs in this group include drugs based on ceftriaxone, cefilin, cefpiron and others.


The safest group of antibiotics that cause the fewest side effects. The principle of their action is the cessation of protein production for cell construction. What will be the effect (bactericidal or bacteriostatic) depends on the choice of drug and its concentration in the body.

a man is reviewing annotations for antibiotics for prostatitis

Antibiotics from this group are effective against the following bacteria:

  • gonococci;
  • chlamydia;
  • ureaplasma;
  • mycoplasmas.

Not all physicians prescribe drugs in this group for the treatment of prostatitis, because, although the effect is logical to assume, narrow studies have not been conducted on this subject. Drugs in this group include drugs based on azithromycin and clarithromycin.


This is not an antibiotic in its classical sense, because an antibiotic is a drug of natural origin or its closest synthetic partner. Fluoroquinolones have no analogues in nature.

Medications of this particular group are most often prescribed by urologists. And there is a good reason for this:

  • First, they have a very broad spectrum of bacterial action, not inferior to natural antibiotics with fewer side effects.
  • Second, they have a very active antimicrobial effect: they affect both DNA production, inhibit its replication, and topoisomerase (an important part of viral integration into cells), and RNA, and cell membrane walls and other processes. which ensures vital activity and the process of cell division - a massive attack from all parts has good results.

Fluoroquinolones are effective against:

  • intestine and Pseudomonas aeruginosa;
  • staphylococci;
  • gonococci;
  • mycoplasmas;
  • chlamydia and other bacteria.

Antibiotics of this group are used for the complex treatment of Koch's bacillus. Therefore, before you start taking these medications, it is important to make sure that there are no tuberculosis-causing agents in the body. The fact is that the intake of separate fluoroquinolones helps Koch's stems develop resistance to other antibiotics, and the process of treating tuberculosis becomes more complicated.

The most effective antibiotic for prostate inflammation

Even the most effective antibiotics will be useless and even dangerous if the reason for choosing this drug is advertising, the opinion of incompetent people who have been helped by this drug, or the fact that this drug was effective last time. No drug is active against all bacteria and viruses, but each group of antibiotics has its best representatives.

Principles and general characteristics of antibiotic therapy for acute and chronic prostatitis

The treatment regimen and drug choice depend on the form of prostatitis. There are similarities and differences in the treatment of acute and chronic prostatitis.

For treatment with antibiotic therapy of any type of prostatitis, the following aspects are characteristic:

  • contacting a doctor and passing a test to identify pathogens is mandatory;
  • treatment should be continued according to the scheme, although it appears that complete recovery has come.

At the same time, when choosing a drug for the treatment of inflammation, you need to take into account several different factors. Therefore, for the treatment of chronic prostatitis, the ability of the active substance to penetrate into prostate cells is fundamentally important. It has been shown that only high concentrations of the drug in the blood are not enough. Not all broad -spectrum drugs, even the latest generation, have such abilities. The situation is different when it comes to acute inflammation: it increases the permeability of prostate cells to the entry of drugs from the blood.

The ability of drugs to penetrate and accumulate in tissues is of fundamental importance in chronic inflammation, but less important in acute inflammation.

The second difference is that the acute phase should be treated as soon as possible, given the severity of the condition. Therefore, preference is given to bactericidal drugs (fluoroquinolones), rather than bacteriostatics. In cases where the principle of action of the drug depends on the dose, the concentration of the drug in the blood and prostate should be sufficient to maintain the effect of bacteria - this applies to drugs from the macrolide group.

Bacteriostatic antibiotics are selected for the treatment of chronic inflammation, and bacterial antibiotics for acute inflammation.

Natural antibiotics: effectiveness and methods of use

Since almost all antibiotics are of natural origin (or are the closest analogues), it is logical to assume that herbs have similar effects with better tolerance and fewer side effects.

However, if the action of herbs is sufficient, there is no need for the production of drugs. Therefore, herbal therapy with antibacterial properties is only suitable as an additional treatment or preventive measure for chronic inflammation of the prostate gland.

There are several herbs that can fight bacteria:

  • yarrow (can have both bacterial and bacteriostatic effects on E. coli and enterobacteria);
  • bitter wormwood (effective against Escherichia and Pseudomonas aeruginosa);
  • eleutherococcus (against white staphylococcus aureus, E. coli and enterobacteria);
  • large plantain (fights white staphylococcus, enterobacteria, has a bacteriostatic effect on proteus, has analgesic effect).

There are many recipes where you can prepare antibacterial drugs to relieve inflammation. Instead of herbs it is better to prepare infusions that do not require prolonged exposure to temperature.

herbal decoction as a natural antibiotic for prostatitis

For almost any herb, the following recipes are suitable:

  1. For one part herb, take ten parts of water at room temperature.
  2. Heat the mixture for a quarter of an hour in a boiling water bath.
  3. Infusion for 45 minutes.
  4. Pass the filter, like gauze.

The infusion is most effective if taken immediately after preparation.

In addition, to combat prostatitis, hazel bark, aspen and chestnut bark are used. From such ingredients is better to prepare decoctions. Each plant has its own recipe, but in general, the preparation of the decoction is as follows:

  1. Wash and grind the raw materials.
  2. Add water so that it completely covers the branches or bark.
  3. Boil in a water bath for half an hour.
  4. Let cool for 10 minutes and drain the broth, squeezing the raw ingredients.

The broth can be taken within 2 days from the moment of preparation.

The effectiveness of treatment depends on several factors: the choice of the desired natural antibiotic, the acquisition of high -quality raw materials (it is better to prepare them yourself) and the preparation of the correct infusion or decoction.

Antibiotics for prostatitis are selected depending on the infection causing the inflammation, the form of the disease and the general health of the patient. Each medication has contraindications and side effects, so you should consult a urologist before taking it. The same is true for medicinal herbs with antibacterial effects.